Usually, although not always, rheumatoid arthritis affects several joints at the same time. In general, RA affects the small joints of the hands, wrists, and fingers as well as the balls of the feet and toes. Joints in the hips, knees, ankles, shoulders, and elbows are also commonly inflamed. This condition where four or more joints are involved is called polyarthritis.
There are some cases of RA where less than four joints are affected. This condition where fewer joints are inflamed is referred to as oligoarthritis. In rarer cases, only one joint is involved. When only a single joint is affected, it is referred to as monoarthritis. Both oligoarthritis and monoarthritis are common in juvenile rheumatoid arthritis (childhood inflammatory arthritis).