Causes Of Liver Disease: Genetics And Medical Conditions
Amazonaws
Genetics, immune system abnormalities, bile and blood flow abnormalities, infectious hepatitis, and certain cancers can cause liver disease.
-
Genetic liver diseases, such as alpha-1 antitrypsin deficiency, hemochromatosis, Wilson’s disease, and Gilbert syndrome, may lead to liver inflammation, cirrhosis, liver cancer, and liver failure.
-
Autoimmune liver diseases, such as primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), and autoimmune hepatitis, may also cause liver inflammation and cirrhosis.
-
Bile flow abnormalities may cause bile to back up into the liver and damage liver cells.
-
Blood flow abnormalities, such as the very rare Budd Chiari syndrome, cause blood clots to form in the hepatic vein and prevent blood from leaving the liver, leading to cirrhosis and liver failure.
-
Common liver infections, such as Hepatitis A, Hepatitis B, and Hepatitis C, can cause liver inflammation.
-
Hepatocellular carcinoma and cholangiocarcinoma are primary cancers that involve the liver.
-
Secondary cancer of the liver or metastatic cancer that begins in one organ and spreads to the liver, such as breast, lung, large intestine, and stomach cancer, as well as leukemia and Hodgkin’s lymphoma, may also involve the liver.
